The effects of methedrine and of lysergic acid diethylamide on mental processes and on the blood adrenaline level.

Lysergic acid diethylamide: side effects and complications.

Pharmacokinetics and Concentration-Effect Relationship of Oral LSD in Humans

BACKGROUND The pharmacokinetics of oral lysergic acid diethylamide are unknown despite its common recreational use and renewed interest in its use in psychiatric research and practice. METHODS We characterized the pharmacokinetic profile, pharmacokinetic-pharmacodynamic relationship, and urine recovery of lysergic acid diethylamide and its main metabolite after administration of a single oral...

Antagonism of histamine-activated adenylate cyclase in brain by D-lysergic acid diethylamide.

D-Lysergic acid diethylamide and D-2-bromolysergic acid diethylamide are competitive antagonists of the histamine activation of adenylate cyclase [ATP pyrophosphate-lyase (cyclizing); E.C. 4.6.1.1] in broken cell preparations of the hippocampus and cortex of guinea pig brain. The adenylate cyclase is linked to the histamine H2-receptor. Both D-lysergic acid diethylamide and D-2-bromolysergic ac...

The Effects of D-lysergic Acid Diethylamide Tartrate (lsd-25) on the Cholinesterases and Monoamine Oxidase in the Spinal Cord: a Possible Factor in the Mechanism of Hallucination.

Relation between Proepileptic Activity of Indomethacin and Adrenal Gland Hormones

The role of inflammation has been shown in the pathogenesis of epilepsy, while glucocorticoids and adrenaline have anti-inflammatory effects. The aim of the present study was to investigate the effects of adrenaline, prednisolone, and indomethacin on caffeine-induced epilepsy (epileptiform activity) in rats and to examine the mechanism of the pro-epileptic effect of indomethacin. The adrenalect...